Hyaluronidase Injections NYC

Hyaluronidase is an injectable enzyme used to reverse the effects of hyaluronic acid fillers. Dermal fillers are more popular than ever due to their ease of access, the lack of downtime and side effects, and the consistently stunning rejuvenation results achieved. As much as dermal fillers have been a boon to cosmetic dermatology, there are times when patients may feel dissatisfied with the final results of their hyaluronic acid fillers. Too often, dermal fillers are injected by untrained or inexperienced injectors, leaving patients with poor cosmetic results. Improper injection techniques can leave patients unhappy with their cosmetic filler injections and can even cause them to want to have their treatment reversed. If you are dealing with an “overdone” look or are otherwise unhappy with the results of your hyaluronic acid fillers, having hyaluronidase injections with Dr. Michele Green in NYC can reverse the effects.

Hyaluronidase injections are the best solution to poor results of hyaluronic acid filler injections. By injecting hyaluronidase into unwanted areas of hyaluronic acid fillers, these cosmetic injections can be dissolved and reversed. Through hyaluronidase injections, your skin can be restored to its original pre-injection condition. If you need to have cosmetic injections of Restylane or Juvederm dissolved, hyaluronidase injections may be the best solution for you. Hyaluronidase needs to be injected into the appropriate locations in precise amounts to ensure optimal cosmetic results and prevent unwanted side effects. An experienced injector, such as Dr. Green in NYC, should always perform hyaluronidase injections.

Dr. Michele Green is an internationally renowned board-certified dermatologist with over two and a half decades of experience providing some of the world’s most discerning individuals with the best non-invasive cosmetic treatment options, including dermal fillers and hyaluronidase injections. As an expert injector, Dr. Green takes a holistic approach and embraces a less-is-more philosophy regarding facial rejuvenation, customizing each patient’s treatment plan best to suit their particular skin concerns and overall aesthetic goals. She is consistently identified as one of New York City’s best dermatologists by Castle Connolly, New York Magazine, and Super Doctors for her dedication to her patients and expertise. If you need to correct misplaced hyaluronic acid fillers, Dr. Green can help.

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What is Hyaluronidase?

Hyaluronidase is an enzyme that occurs naturally in the body, and it is produced by white blood cells to move more quickly through connective tissues in the body. Hyaluronidase enzymes have been discovered in insects, mammalian tissues, and even snake venom. There are a variety of different hyaluronidase classifications, with the most common being Hyal1 and Hyal2. Hyaluronidase activity within Hyal2 has less enzyme activity but is, in fact, able to break down hyaluronic acid with a higher molecular weight. Hyaluronidase is an injectable enzyme that is marketed with several FDA-approved brand-name formulations, including Hydase, Hylenex, Amphadase, and Vitrase. Hyaluronidase injections typically contain this enzyme collected from purified bovine tissue (ovine testicular hyaluronidase) or derived from human albumin sources (recombinant human hyaluronidase).

The injections of hyaluronidase are often used to dissolve hyaluronic acid dermal fillers and reverse poor cosmetic results. Hyaluronidase injections are used to break down or reverse hyaluronic acid fillers and work fairly quickly, usually within 24 hours. Sometimes, it may be necessary to return for a second or third round of treatment with hyaluronidase, depending on the type and amount of hyaluronic acid filler that was initially used. Hyaluronidase does not work on non-hyaluronic acid fillers, such as Radiesse or Sculptra, and you will need to discuss options with Dr. Green beforehand, as results vary per patient. At her private dermatology office in Manhattan’s Upper East Side neighborhood, Dr. Green uses Hylenex, a synthetic, recombinant DNA product made from human products. Recombinant human hyaluronidase has a purity 100 times higher than some of the bovine preparations, and allergic reactions to Hylenex are very rare.

What does hyaluronidase do?

Hyaluronidase has a variety of FDA-approved medical functions, including improving the diffusion of anesthetics in pain therapy, aiding in the absorption of treatment agents in chemotherapeutics and ophthalmic surgery, as a spreading agent in subcutaneous injections, and off-label in dissolving hyaluronic acid fillers. Different types of hyaluronidase work through different mechanisms of action, meaning the biochemical reactions that occur when hyaluronidase reacts with other substances in the body vary depending on the specific hyaluronidase enzyme used. Hyaluronidase derived from mammals and leeches breaks down glycosidic linkages via the process of hydrolysis, which is when a chemical reaction occurs with the help of water to break a compound down. By breaking down the glycosidic linkages of hyaluronic acid, hyaluronidase leads to the decreased viscosity, or thickness, of hyaluronic acid molecules, contributing to the removal of the hyaluronic acid in the treatment area, making it a highly effective treatment to reverse the effects of poorly executed hyaluronic acid fillers.

Where does hyaluronidase come from?

Hyaluronidase is a natural enzyme found in both bovine and human albumin; it is isolated and purified before being used as an injectable drug in the medical field. Hyaluronidase is a highly complicated substance to create in injectable form and should never be attempted to be made at home. Hyaluronidase should only ever be administered by a board-certified medical professional, and only FDA-approved brands should be used. These brands include Hydase, Hylenex, Amphadase, and Vitrase. Under no circumstances should hyaluronidase be used from an unverified source. Brands like Hylenex use hyaluronidase derived from human albumin sources, which minimizes the risk of an allergic reaction. Dr. Green typically uses the Hylenex formulation for her hyaluronidase treatments, as she has found that its formulation is reliable and consistent for a wide variety of patient needs.

What is Hylenex?

Hylenex is one of the FDA-approved brand names for injectable hyaluronidase. Vitrase, Amphadase, and Hydase are all other common brand names for hyaluronidase. These brands can be used interchangeably to remove unwanted HA filler or those that have migrated, though some of the properties differ between formulations. The effects of hyaluronidase should be consistent, regardless of which hyaluronidase injectable is used to remove your hyaluronic acid fillers. Hylenex is unique from other available FDA-approved hyaluronidase injectables in that it is the only product that does not include any materials derived from animal products. Since Hylenex is a recombinant human hyaluronidase, there is no risk of an allergic reaction to the injections. Hyaluronidase products that are derived from animal products can rarely cause an allergic reaction. Dr. Michele Green has over two and a half decades of experience with cosmetic injectables, including hyaluronic acid dermal fillers and hyaluronidase, and prefers to use Hylenex.

What is Hyaluronic acid?

Hyaluronic acid, also referred to as hyaluronan, is a naturally occurring substance in the body that stimulates collagen production in the skin and plays a key role in moisture retention and structure. Hyaluronic acid is a glycosaminoglycan, which is considered a major component of the extracellular matrix, as it links together collagen fibers, connective tissue, and protein filaments in the body. Hyaluronic acid is formed by a polymer of two primary disaccharides, D-glucuronic acid and D-N-acetylglucosamine. Hyaluronic acid filler injections are commonly used to boost the volume of the skin via subcutaneous injections, and many hyaluronic acid fillers use hyaluronate cross-linking technology. These linkages connect hyaluronic acid molecules with a plasticizing agent for optimal facial contouring.

Hyaluronic acid-based fillers boost the volume in the treatment area by attracting water and encouraging collagen production. HA fillers are a great option for patients interested in achieving a rejuvenated appearance. Dr. Green often uses hyaluronic acid fillers to treat a variety of cosmetic concerns without the need for plastic surgery, including:

• The reduction of fine lines and wrinkles around the eyes and mouth, including marionette lines, smile lines, and perioral lines
• Lip augmentation
• Chin augmentation
• Jowl correction
• Cheek augmentation and Correction of age-related volume loss in the midface
• Correction of age-related volume loss under the eyes to reduce the appearance of dark circles or under-eye bags
• Volume loss in the hands
• Buttock augmentation
• Hip Dip correction
• Necklines

Some of the most popular brands of hyaluronic acid fillers include Juvederm, Restylane, and Belotero. When you consult with expert cosmetic dermatologist Dr. Green regarding filler treatment, she will physically evaluate your face and collect a complete medical history prior to creating a treatment plan for you. Dr. Green takes a holistic approach to facial rejuvenation treatment and tailors each of her patients’ dermal filler injections to meet each patient’s concerns best, embracing an artful, “less-is-more” philosophy when it comes to her dermal filler injections.

It is important to understand the qualifications of your cosmetic injector and the exact type of dermal filler that you are choosing in order to guarantee that your cosmetic results are satisfactory, performed in a safe and sterile manner, and to avoid any complications or unwanted side effects. Dr. Green embraces a less-is-more philosophy regarding dermal fillers, and she is dedicated to the satisfaction of her patients. She works to make sure that each of her patients is completely satisfied with their dermal filler results so that they look and feel like the very best version of themselves. For men and women who come to her frustrated by a previous hyaluronic acid filler experience, she is able to offer hyaluronidase treatment, which can dissolve the effect of overdone or unwanted hyaluronic acid filler results.

How does hyaluronidase work?

Hyaluronidase is an enzyme that breaks down the linkages between hyaluronic acid molecules. It is typically injected subcutaneously to reverse previous cosmetic injections of hyaluronic acid fillers such as Restylane or Juvederm and other dermal filler treatments. The Hyaluronidase enzyme decreases hyaluronic acid from the dermal filler, ultimately reversing its cosmetic effects. Patients should always wait at least two weeks after their dermal filler injections to consider hyaluronidase, as the fillers can take up to two weeks to settle.

The process of getting hyaluronidase injections is simple and convenient. First, you will be able to meet with Dr. Green to talk about your concerns with your current hyaluronic acid filler results, as well as your medical history, and work together to develop a treatment plan that will best meet your needs. Dr. Green will ask about the amount and type of hyaluronic acid fillers you are interested in dissolving. Then, for your hyaluronidase injection procedure, Dr. Green will administer hyaluronidase to the initial hyaluronic acid filler treatment area to reverse its effects. After your treatment, you can resume normal activity, as this procedure requires no downtime. Some potential side effects include swelling, bruising, and tenderness at or near injection sites, which resolve independently one to two weeks after the hyaluronidase injections. The effects of hyaluronidase are usually apparent after just 48 hours. For most patients, the appearance of the previous dermal filler will be completely reversed after one treatment, though some patients may need a second or third hyaluronidase treatment. Dr. Green will ask you to return to her office two weeks after your initial hyaluronidase injections to evaluate the results and determine whether any touch-up is required.

40-49 year old – Hyaluronidase 2 weeks before and after

What is hyaluronidase used for?

The use of hyaluronidase injections is approved by the Food and Drug Administration (FDA) for a variety of treatments and is commonly used for the following:

• for fluid infusion through subcutaneous tissues (known as hypodermoclysis), particularly within pediatric care.
• as an adjuvant to accelerate the diffusion of drugs and local anesthetics subcutaneously in regard to both dispersion and delivery
• as an adjunct in promoting absorption of contrast agents (dye) in urography (x-ray of blood or lymph vessels in the urinary tract)
• as a method of edema reduction (off-label use)
• as a treatment of vitreous hemorrhage
• as a treatment for extravasation (fluid leakage) within chemotherapy patients to prevent tissue necrosis (cell death)
• for retrobulbar anesthesia within ophthalmic surgery
• to dissolve the effects of hyaluronic acid fillers, particularly incited by an allergic reaction, delayed-onset nodules, HA-incited blindness, Tyndall effect (blueish hue to the skin), vascular occlusion, or an unacceptable cosmetic outcome.

According to an in vitro study by Rao et al., hyaluronidase is successful in reversing the effects of most popular hyaluronic acid fillers, though the amount of hyaluronidase needed to dissolve the fillers varied by formulation. The study looked at two hyaluronidase formulations and four hyaluronic acid fillers that are commonly used in the United States and found hyaluronidase effective at reversing the effects of the fillers in each case. For additional clinical information on hyaluronidase, there are many articles of note on Pubmed, in particular in the Journal of Cosmetic Dermatology and Dermatol Surg.

How much hyaluronidase to dissolve fillers?

The precise amount of hyaluronidase required to dissolve your hyaluronic acid filler and reverse its effects can vary depending on the type and amount of hyaluronic acid dermal filler that was initially injected during your facial rejuvenation treatment. If several syringes of HA filler were injected during a dermal filler treatment session, then a patient may require multiple vials of hyaluronidase to dissolve the filler product completely. Generally, a one-to-one ratio of hyaluronidase to hyaluronic acid dermal filler is required to dissolve the product fully. However, each patient is different and may require more hyaluronidase to dissolve their filler fully. In the case of hyaluronic acid fillers that utilize cross-linking technology, multiple treatment sessions with hyaluronidase may be needed to break down the many linkages between the hyaluronic acid molecules.

While clinical trials have shown that hyaluronidase injections are safe and effective for reversing the effects of HA dermal fillers, current literature diverges in terms of recommended hyaluronidase doses. For this reason, it is recommended to rely on expert opinion and to use moderation in the application of hyaluronidase. Dr. Michele Green in NYC tailors hyaluronidase injection treatments based on her expertise and extensive knowledge of hyaluronic acid fillers. For each patient that she treats with this injectable, she offers and encourages a follow-up appointment, scheduled approximately two weeks after an initial hyaluronidase treatment with her, to determine whether a second (or third) hyaluronidase injection procedure is needed to get the best results.

How long does it take to dissolve filler with hyaluronidase?

The effects of hyaluronidase will begin to appear within two to three days of the hyaluronidase injections. However, the amount of time it will take for the full effect of hyaluronic acid filler reversal varies depending on the individual patient. The majority of patients see complete results from hyaluronidase injections within two weeks. However, some may need two or more weeks in order to appreciate the full results of the hyaluronidase treatment. It is best to wait two weeks to determine your cosmetic results and to determine if additional hyaluronidase is needed. Hyaluronidase injections can cause swelling at the site of injection as well.

After the hyaluronidase takes full effect, some patients may feel that they’d like to boost their collagen production through alternative means aside from dermal fillers. In this case, Dr. Green can help develop a revitalizing skincare treatment plan, which can range from laser resurfacing, radiofrequency lasers such as Thermage and Vivace, chemical peels, and microneedling. Dr. Green is an expert in cosmetic dermatology and anti-aging techniques and can help you both look and feel like your best self.

Is hyaluronidase safe?

Yes! Hyaluronidase is FDA-approved, meaning it has been proven to be safe and effective for use. Similarly to Juvederm and Restylane, injections of hyaluronidase are safe and have minimal side effects. That said, you could potentially look at testing it gradually via multiple treatment sessions, which can be arranged with cosmetic dermatologist Dr. Green in New York. Unlike procedures that use alternative substances such as Radiesse, Sculptra, or silicone oil fillers, hyaluronic acid fillers can be dissolved immediately after the procedure is done or months later. It is always important to have your hyaluronidase injections with an experienced board-certified dermatologist like Dr. Green to ensure that you get the best results while limiting potential side effects. Hyaluronidase must be injected into the appropriate areas in precise amounts to prevent dissolving natural hyaluronic acid, which can result in crepey skin. Dr. Green is an expert injector with over 25 years of experience and will work with you to achieve your ideal aesthetic results.

Does hyaluronidase have any side effects?

Side effects of hyaluronidase are rare. The most common side effects include mild swelling, bruising, and tenderness at or near injection sites, which can be expected to resolve independently within one week of hyaluronidase injections. Another potential side effect of hyaluronidase is a mild allergic reaction near the injection site for patients with a hypersensitivity to the treatment. It is rare to have an allergic reaction, with a reported incidence of allergic reaction being between 0.05% and 0.69%. A skin test may be performed before your hyaluronidase injections to evaluate for hypersensitivity. Recent studies have shown that hyaluronidase is antigenic, which means that repeated hyaluronidase injections of relatively large amounts may lead to the production of neutralizing antibodies. This means that hyaluronidase will not necessarily continue to be as effective in dissolving hyaluronic acid filler with large amounts of use. Additionally, hyaluronidase should not be injected via intravenous injections, as this can put patients at risk for allergic reactions and more adverse events.

Occasionally, patients may observe a “depleted” look due to a temporary dip in the natural hyaluronic acid stores within the body. However, your body will replenish its natural hyaluronic acid and return to its normal level over the next few hours to days. If, after several weeks, your skin continues to appear depleted or sagging, Dr. Green can suggest a non-invasive cosmetic procedure to help stimulate collagen production within the body to offset these undesirable effects. In this case, Dr. Green can work with you to develop a customized treatment plan. Collagen-stimulating treatments include laser resurfacing, Thermage, Microneedling, and chemical peels, among others are excellent options for revitalizing depleted-looking skin.

Does hyaluronidase dissolve natural hyaluronic acid?

Hyaluronidase is a natural enzyme often used to dissolve unwanted hyaluronic acid fillers; however, it can also dissolve natural hyaluronic acid. The injectable treatment will target the linkages between hyaluronic acids in the designated treatment area, which will consist primarily of hyaluronic acids from fillers. The hyaluronidase will target hyaluronic acid from dermal fillers prior to dissolving any natural hyaluronic acid. Additionally, hyaluronic acid is a substance that is constantly produced and dissolved by the body as a part of the body’s natural ebb and flow. Even if the hyaluronidase injection dissolves natural hyaluronic acid, your body will be able to restore your natural hyaluronic acid to its pre-filler level in very little time. Dr. Green will determine the appropriate amount of hyaluronidase for each injection depending on the amount of dermal filler that was previously injected. Dr. Green’s experience as a cosmetic injector ensures that the amount of hyaluronidase is safe and appropriate and reduces the risk of any unwanted side effects.

Does hyaluronidase destroy your natural tissue?

Hyaluronidase does not dissolve your natural tissue. Though hyaluronidase can dissolve your body’s natural hyaluronic acid, it is not able to dissolve tissue. Hyaluronidase, either naturally occurring within the body or as an injection, breaks down hyaluronic acid and only hyaluronic acid, which is a component found in the skin. Tissue is made of cells that are broken down through different pathways than hyaluronic acid. Occasionally, patients might observe a “depleted” appearance on their skin after hyaluronidase treatment. This is due entirely to the temporary depletion of natural hyaluronic acid. After a hyaluronidase injection, the skin will typically restore its hyaluronic acid levels within a few days or, in rare cases, over a few weeks.

As hyaluronidase can dissolve natural stores of hyaluronic acid, it is incredibly important that an experienced, board-certified medical professional be relied upon to determine the amount of hyaluronidase necessary to reverse the effects of a hyaluronic acid filler. Dr. Green personally develops all hyaluronidase treatment plans and determines the correct amount for each patient. Her “less is more” approach is applied to both dermal filler and hyaluronidase treatment in order to optimize the effects of cosmetic injectable treatments and avoid any dissatisfaction. Dr. Green’s top priority is the safety and satisfaction of all her patients.

Two treatments of Hyaluronidase under the eyes to dissolve improper Juvederm injections under her eyes (tear troughs)

Does hyaluronidase spread? How far does hyaluronidase spread?

Hyaluronidase does spread to a certain degree into the tissue. In fact, one of the main roles of hyaluronidase in the medical field is to help with the diffusion, or spreading, of drugs or agents injected into the tissue. Diffusion can be defined as how well or how far a substance can spread. Hyaluronidase is a highly effective substance to accompany treatments in the medical field as it can help to increase the permeability of cells and blood vessels into which drugs or chemical agents need to be absorbed and increase the dispersion of those drugs or agents. For example, according to a review done by Cavallini et al. (https://doi.org/10.1177/1090820X13511970), hyaluronidase is often used during chemotherapy to assist with the permeation of the treatment drug into a malignant tumor. Hyaluronidase can also be used in the field of radiology to aid with the diffusion and absorption of the agent used to provide healthcare workers with a better view of the treatment area. In ophthalmic surgery and pain therapy, hyaluronidase is also used to help the anesthesia spread throughout the treatment area.

What is the Cost of Hyaluronidase Treatment?

The cost of hyaluronidase varies depending on the amount of filler needed to be dissolved. The average treatment cost is around $1,000. When you have a consultation with Dr. Green, we will be able to give you a more accurate quote. When you work with Dr. Green in NYC, she will carefully assess your concerns about hyaluronic acid filler and provide you with a treatment plan that best fits your budget and individual needs.

Hyaluronidase: 2 weeks under eyes – before and after

How to use hyaluronidase?

Hyaluronidase should only be injected by a trained medical provider. If you have unwanted or poorly injected hyaluronic acid fillers, an experienced, board-certified dermatologist such as Dr. Michele Green can dissolve them. Having unwanted or unsatisfactory hyaluronic acid fillers dissolved with hyaluronidase is a quick and straightforward cosmetic procedure. To have your HA fillers dissolved with hyaluronidase, you must first meet with Dr. Michele Green for a consultation at her private dermatology office in the Upper East Side neighborhood of Manhattan. She will review your medical history, history of cosmetic treatments, including dermal fillers, and your specific skin care concerns and aesthetic goals. Treatment with hyaluronidase injections may be performed on the same day as your consultation or scheduled for a later date.

When it comes time for treatment, the skin will be sterilized, and Dr. Green will quickly and artfully perform the hyaluronidase injections. Patients note that the Hylenex injections may sting somewhat, though the injections themselves are quickly performed, and the discomfort is both minimal and brief. Once injected, the hyaluronidase begins working immediately to break down the hyaluronic acid fillers, restore the patient’s appearance, and dissolve the previously injected HA dermal fillers. Although hyaluronidase begins working as soon as it is injected, it may take up to 14 days to see the full results of treatment after the initial injection. For this reason, Dr. Green typically recommends that her patients return to her office about two weeks after hyaluronidase injections. During this follow-up visit, it will be determined whether any additional hyaluronidase is required to dissolve the dermal fillers completely. Once all fillers are dissolved, a cosmetic treatment plan for future dermal fillers will be discussed with Dr. Green.

Does hyaluronidase hurt?

Hyaluronidase injections are relatively pain-free. Some patients report a slight stinging sensation during the injections, which resolves shortly after the injection. Common side effects can include mild swelling, bruising, and tenderness at or near injection sites, which tend to resolve independently within 48 hours of the treatment. Patients with sensitive skin may choose to apply a topical numbing cream one hour before their injections. Dr. Green will prescribe the lidocaine cream to the pharmacy of your choice. Once you arrive at Dr. Green’s private dermatology office in Manhattan’s Upper East Side neighborhood, the lidocaine cream will be removed, and the skin will be sterilized. Ice packs will be applied to the treated area immediately after the hyaluronidase injections to minimize any swelling or bruising.

Will hyaluronidase dissolve all fillers?

Hyaluronidase effectively dissolves any hyaluronic acid fillers, including popular fillers from the Juvederm and Restylane families. However, dermal fillers composed of other substances, such as poly-l-lactic acid or calcium hydroxylapatite, cannot be dissolved with hyaluronidase. For this reason, it is imperative that an experienced board-certified dermatologist, such as Dr. Michele Green in NYC, always perform your cosmetic injections to ensure the safety and efficacy of the treatment. Dr. Green has over two and a half decades of experience providing some of the world’s most discerning individuals with the best non-invasive cosmetic treatment options, including dermal filler and hyaluronidase injections. Dr. Green takes a holistic approach and embraces a less-is-more philosophy regarding facial rejuvenation, customizing each patient’s treatment plan to cater best to their particular skin concerns and aesthetic goals.

Frequently Asked Questions About Hyaluronidase:

What is hyaluronidase injection used for?

Hyaluronidase injections have many purposes. As an endoglycosidase, hyaluronidase breaks apart the chains of hyaluronic acid molecules so that they can be removed from the skin. This function allows hyaluronidase to have broad applications in the medical field. Hyaluronidase is most often used to dissolve HA dermal fillers and to improve the dispersion of drugs that are injected into the skin. Besides cosmetic use, hyaluronidase is used as an adjunct in subcutaneous urography for improved resorption of radiopaque agents. To learn more about the various approved uses of hyaluronidase injections, you can view the label on the FDA website.

How long does it take for hyaluronidase to dissolve filler fully?

Hyaluronidase works quickly and effectively to dissolve unwanted hyaluronic acid filler in the treatment area. Many patients start to see the treatment’s effects 2-3 days after the procedure, with full effects being visible around two weeks post-treatment. However, results vary due to the different degrees of density of hyaluronic acid fillers. Some fillers may require an increased amount or repeated number of treatments to dissolve them. There will be some swelling at the injection site, which can last for up to two weeks. For that reason, Dr. Green recommends having patients wait two weeks before returning to the office for a follow-up appointment, where Dr. Green can assess the effectiveness of the first hyaluronidase treatment and potentially recommend a second or third treatment session.

How long after hyaluronidase can I get dermal fillers?

Patients should wait at least two weeks after their last hyaluronidase injections before having dermal fillers. By waiting two weeks, patients allow any side effects of the hyaluronidase injections, such as swelling, bruising, or tenderness at or near injection sites, to resolve. If you have hyaluronic acid filler injections too soon after hyaluronidase injections, there is a potential risk of the hyaluronidase dissolving the new dermal fillers. Dr. Green recommends that her patients fully reverse the effects of their previously injected hyaluronic acid fillers before having facial rejuvenation with cosmetic injectables so that they get the optimal cosmetic results from their treatment. When you consult with Dr. Green, she will work with you to establish a treatment plan and timeline that works best for you.

How to dissolve filler without hyaluronidase

Hyaluronidase is the only effective and safe treatment method when it comes to dissolving hyaluronic acid dermal fillers and reversing their effects due to its enzymatic properties of degrading hyaluronic acid. Additionally, dermal fillers that are not composed of hyaluronic acid cannot be dissolved with hyaluronidase injections. Patients who have been injected with dermal fillers that are composed of material other than hyaluronic acid, such as Radiesse (calcium hydroxylapatite) and Sculptra (poly-L-lactic acid), must wait for the effects of these dermal fillers to wear off over time. For this reason, it is imperative to be treated with cosmetic injectables by a board-certified cosmetic dermatologist who has both the expertise and the experience to perform your facial rejuvenation. Dr. Green always gives her patients long-lasting, natural-looking results that leave them looking and feeling like their absolute best.

Does hyaluronidase dissolve Botox?

Botox is the gold standard for reducing dynamic fine lines and wrinkles. However, it cannot be dissolved by hyaluronidase. Botox is a neurotoxin, not a hyaluronic acid dermal filler. Only hyaluronic acid fillers can be dissolved with hyaluronidase. As a neurotoxin, Botox inhibits nerve signals to certain facial muscles related to expression, essentially “freezing” them. This prevents them from overuse, ultimately leading to a smoother skin texture and a reduction in visible fine lines. The effects of Botox typically last up to four months, with most patients engaging in regular treatment sessions to maintain the best results.

Does hyaluronidase dissolve Restylane?

Yes! Restylane fillers are a popular brand of hyaluronic acid fillers that can be dissolved with hyaluronidase if desired. They are a great option for adding volume and enhancing facial features; however, when untrained or inexperienced injectors perform the dermal filler, there is a chance for poor cosmetic results. Patients who have unsatisfactory Restylane results can consult with Dr. Green, who can create a hyaluronidase treatment plan that fits their aesthetic needs and goals.

What can go wrong with hyaluronidase?

There are very few adverse effects of hyaluronidase. The most common side effect of hyaluronidase injections is mild swelling and bruising at or near the injection site. The swelling and bruising associated with Hylenex injections will resolve independently in one to two weeks. Rarely do some patients have an allergic reaction to the injections, which usually occurs locally as hypersensitivity but can occur as a systemic reaction. Overall, injections with hyaluronidase are incredibly safe, with minimal risk for adverse reactions.

Can Hyaluronidase cause permanent damage?

Injections with hyaluronidase cannot cause permanent damage. Hyaluronidase can cleave the chains of hyaluronic acid often found in dermal fillers before breaking down natural hyaluronic acid. Because our bodies naturally create and destroy hyaluronic acid to maintain homeostasis, the body can reform any naturally occurring hyaluronic acid that was dissolved by the hyaluronidase. After hyaluronidase injections, the skin will normalize the amount of hyaluronic acids to its pre-filler level.

Does hyaluronidase damage the skin?

Hyaluronidase will not affect the skin’s natural collagen or otherwise damage the tissue. Hyaluronidase is specifically used for dissolving hyaluronic acid fillers. Hyaluronidase may dissolve some of the skin’s natural hyaluronic acid, potentially causing a slightly crepey skin texture in the treated area. This crepey skin will resolve independently after a few days. Side effects of hyaluronidase injections can include tenderness, bruising, and swelling at or near injection sites. It is always recommended to have hyaluronidase injections with an experienced board-certified dermatologist, such as Dr. Green in New York City, to ensure you obtain the best cosmetic results while limiting the potential side effects. Dr. Green is an expert injector with over two and a half decades of experience providing some of the world’s most discerning individuals with the best non-invasive treatment options available. If you’ve had dermal fillers that need correction, Dr. Green is here to help.

Does Hyaluronidase dissolve your own skin’s tissue?

Hyaluronidase does not dissolve tissue; rather, it dissolves hyaluronic acid, a substance that plays a part in water retention and structure. The injectable treatment will not harm the skin’s tissue and cells; it only interacts with hyaluronic acid. After hyaluronidase injections to correct dermal filler injections, there may be some side effects, such as swelling or bruising, but these will resolve within two weeks of the procedure. For the safest injections, it is always recommended to consult with an experienced, board-certified dermatologist, such as Dr. Green.

Does hyaluronidase dissolve fat?

Hyaluronidase does not dissolve fat. However, it is an effective way to dissolve hyaluronic acid, and hyaluronidase injections are specifically used to dissolve hyaluronic acid filler injections. Fat cells are dissolved and metabolized within the body by different means, as they are created through different processes in the body. However, fat cells can be metabolized through a variety of non-invasive cosmetic treatments offered by Dr. Green.

A different non-invasive injectable, Kybella, can dissolve fat cells. Kybella is an FDA-approved injectable that dissolves excess fat and is particularly effective for those frustrated by the appearance of a double chin or a stubborn pocket of unwanted fat around the jawline. Kybella uses a synthetic form of deoxycholic acid, a natural substance that helps to metabolize dietary fat in the body. It is able to eliminate fat cells near the injection site, thus preventing these fat cells from further fat accumulation. In this way, Kybella® can actually permanently eliminate fat cells at or near the injection site. Kybella requires little to no downtime and often requires as little as one treatment for optimal results. Most patients require three treatment sessions, spaced one month apart, of Kybella to achieve their ideal cosmetic results. The most common side effect of Kybella is swelling, which resolves on its own within several days of treatment.

Another highly popular method of fat reduction is the CoolSculpting® procedure. CoolSculpting is an innovative body contouring device that uses “fat freezing” techniques (Cryolipolysis) to eliminate excess fat on the body. Though CoolSculpting is not a weight loss technology, it can be an ideal tool for those who have lingering pockets of fat in the abdomen, along the arms, or under the chin, even though they maintain a healthy lifestyle. CoolSculpting is able to “freeze” fat cells at a higher temperature than other cells in the body, and then these frozen cells are metabolized naturally in the body. Over several weeks, these fat cells will be permanently eliminated from the body. CoolSculpting is safe to use on a variety of areas of the body, including the legs, arms, stomach, lower back, upper back, bra area, and under the chin. The procedure requires no anesthesia, recovery, or downtime, and the results are permanent, provided patients don’t experience excessive weight fluctuation post-treatment.

Will Hyaluronidase ruin my face?

Hyaluronidase injections will not ruin your face. These injections will destroy any unwanted hyaluronic acid filler to reveal your pre-filler appearance. To confirm the safest and most effective hyaluronidase treatments, you should consult with an expert, board-certified physician, such as Dr. Green. When you consult with Dr. Green, she will physically evaluate your face and review the previous dermal fillers you have received before artfully creating a hyaluronidase treatment plan that caters to your aesthetic needs and goals.

How to pronounce Hyaluronidase?

Like many medical and scientific terms, hyaluronidase can be difficult to pronounce correctly. The term is the combination of “hyaluronic” and “-idase,” describing an enzyme that breaks down hyaluronic acid. The phonetic pronunciation is: hai·uhl·ur·aa·nuh·days.

Where to buy hyaluronidase?

Hyaluronidase can only be purchased and injected by a licensed medical professional. A patient cannot purchase hyaluronidase from the internet or elsewhere for cosmetic injection.

How to mix hyaluronidase?

Hyaluronidase comes as a vial of one ml liquid solution. When used to dissolve hyaluronic acid dermal fillers, it does not need to be mixed, diluted, or reconstituted before injection into the treated area.

How to reconstitute hyaluronidase?

Hyaluronidase comes in a vial prepared to be injected immediately. Some providers may want to decrease the dilution of the hyaluronidase mixture. To achieve their desired dilution, healthcare providers can draw up a specific amount of bacteriostatic saline and combine it with hyaluronidase.

How to give hyaluronidase for extravasation?

Hyaluronidase can be used off-label to manage extravasation, which occurs when fluids spill from the IV lines during chemotherapy treatment. Specially trained healthcare providers treat extravasation in a hospital setting. When they do so, they inject 4-5 small amounts of hyaluronidase into the edge of the extravasation area. Ultimately, extravasation should only be treated in a hospital setting by experts who can identify the signs and symptoms to treat the medical condition appropriately.

How do I have unwanted dermal fillers dissolved with hyaluronidase today?

If you have had hyaluronic acid filler injections with an inexperienced or unqualified injector and are feeling disappointed with the cosmetic results of your cosmetic injections, hyaluronidase injections with Dr. Green in NYC may be just the solution you have been searching for. Hyaluronidase injections are considered to be the gold standard treatment when it comes to dissolving unwanted or misplaced hyaluronic acid fillers that have produced poor cosmetic results.

Dr. Michele Green is an internationally renowned board-certified cosmetic dermatologist with over two and a half decades of experience providing some of the most discerning individuals with the best non-invasive cosmetic treatments available, including dermal fillers and hyaluronidase injections. Taking a holistic approach and embracing a less-is-more philosophy regarding facial rejuvenation, Dr. Green customizes each patient’s treatment protocol to provide a natural-looking, long-lasting, more youthful appearance.

Her dedication to her patients and her practice is well-reflected by the fact that she is consistently voted as one of NYC’s best physicians by Castle Connolly, Super Doctors, and New York Magazine. When you consult with Dr. Green at her private dermatology office in Manhattan’s Upper East Side neighborhood, she will work with you to create a personalized treatment plan that best suits your particular skin concerns and overall aesthetic goals. To schedule a consultation with Dr. Green, contact the office online today or call 212 535 3088.